Evidence map›Paper›PMID 42613180›Full record

ArticleeNeuro2026

Neuronal

Alexander M Kuhn, Kelly E Bosis, Madeline M Mairose, David T Dadosky, Brandon L M Crotchett, Etienne J Mueller, Kenny Triplett, Lilian Jerow, Lauren Larke Vollmer, Justin L Bollinger and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander M KuhnDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.ORCID https://orcid.org/0000-0002-2424-8452
Kelly E BosisNeuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.ORCID https://orcid.org/0000-0003-2183-9406
Madeline M MairoseDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.ORCID https://orcid.org/0009-0006-2367-865X
David T DadoskyDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.ORCID https://orcid.org/0000-0002-4778-6026
Brandon L M CrotchettDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.ORCID https://orcid.org/0000-0002-9661-2348
Etienne J MuellerDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Kenny TriplettMolecular & Cellular Biosciences, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Lilian JerowNeuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Lauren Larke VollmerDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Justin L BollingerDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267.
Eric S WohlebDepartment of Pharmacology, Physiology, & Neurobiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 eric.wohleb@uc.edu.

Funding

PREDOCTORAL TRAINING PROGRAM IN THE NEUROSCIENCEST32NS007453 · NINDS · UNIVERSITY OF CINCINNATI · PI HERMAN, JAMES P · 1997 to 2025
$4.0M
Defining neuron- and microglia-specific contributions to prefrontal cortex dysfunction in chronic stressR01MH123545 · NIMH · UNIVERSITY OF CINCINNATI · PI WOHLEB, ERIC S · 2020 to 2024
$2.0M
NIMH NIH HHS R01 MH123545NINDS NIH HHS T32 NS007453
6 · The paper itself

Abstract

Chronic stress exposure causes neurobiological and behavioral changes that resemble those reported in psychiatric conditions such as major depressive disorder (MDD). Preclinical stress models and studies using postmortem tissue from MDD patients have shown that DNA damage-inducible transcript 4 (

Indexed as

Cognitive DysfunctionNeuronsPrefrontal CortexSynapsesTranscription FactorsAnimalsDendritic SpinesMaleMiceMice, Inbred C57BLMice, TransgenicMicrogliaStress, PsychologicalDdit4 protein, mouseTranscription FactorsbehaviorDdit4dendritic spinemicrogliaprefrontal cortexRNA sequencing

Identifiers

PMID42613180
PMCPMC13548363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.