Evidence map›Paper›PMID 42612730›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2026

Carbohydrate and Energy Composition of Preterm Human Milk: A Systematic Review and Meta-Analysis.

Derek C Miketinas, Mindy A Patterson, Vanessa K Thyne, Dixie L Carter, Nathan A Meredith, Maria Fernanda Nunez, Katie E Niemeier, Jennifer N Kinnaman, Tonya M Bender, Ariana Dl Bailey

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Derek C MiketinasDepartment of Nutrition and Food Sciences, Texas Woman's University, Houston, TX, United States; Institute for Women's Health, Texas Woman's University, Houston, TX, United States.
Mindy A PattersonDepartment of Nutrition and Food Sciences, Texas Woman's University, Houston, TX, United States; Institute for Women's Health, Texas Woman's University, Houston, TX, United States.
Vanessa K ThyneDepartment of Nutrition and Food Sciences, Texas Woman's University, Houston, TX, United States.
Dixie L CarterGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Nathan A MeredithGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Maria Fernanda NunezGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Katie E NiemeierGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Jennifer N KinnamanGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Tonya M BenderGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States.
Ariana Dl BaileyGlobal Research & Development, Mead Johnson Nutrition, Evansville, IN, United States. Electronic address: ariana.delong13@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm human milk (HM) is a major source of carbohydrates (CHOs), primarily lactose, which contribute to energy intake and support growth and neurodevelopment. This systematic review and meta-analyses quantified total CHO, lactose, and energy content in preterm HM. EBSCO (Health Source-Nursing/Academic Edition and MEDLINE with Full Text), PubMed, and Scopus were searched through July 2023 for studies reporting nutrient composition in preterm HM (<37 wk gestation) from countries with a Human Development Index ≥0.8 to reduce potential heterogeneity that may influence HM composition. Cross-sectional, case-control (n ≥ 1), prospective cohort, and randomized controlled trials published in English were included. Two reviewers independently screened titles and abstracts. Of the studies meeting inclusion criteria, this meta-analysis included articles that reported total CHO, lactose, and energy content in preterm HM. Random-effects models estimated pooled mean amounts of total CHO, lactose, and energy across studies. Heterogeneity was estimated using I

Indexed as

carbohydratecolostrumenergyhuman milklactosematuremilkpretermtransition

Identifiers

PMID42612730
PMCPMC13627815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.