ArticleChemSusChem2026
Curcumin-Enabled Metal-Free Photocatalytic Oxidation of Aryl- and Alkyl-methanamines to Imines Under Green Conditions.
Article in ChemSusChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Herein, we report a fully bio-based, metal-free photocatalytic protocol for the aerobic oxidation of aryl- and alkyl-methanamines to imines under blue-light irradiation. This transformation leverages curcumin, a naturally abundant and renewable polyphenol, as an efficient visible-light photosensitizer and 2-methyltetrahydrofuran (2-MeTHF), a biomass-derived solvent, establishing a sustainable catalytic system composed entirely of organic, bio-derived components. The reaction proceeds efficiently at room temperature using molecular oxygen as the sole terminal oxidant, strictly avoiding transition metals, stoichiometric oxidants, and hazardous additives. A broad range of benzylic and aliphatic amines is converted to the corresponding imines in good to excellent yields (up to 98%), demonstrating the generality and practicality of the protocol. Comprehensive mechanistic investigations-including light on/off experiments, oxygen-dependence studies, radical trapping, Stern-Volmer fluorescence quenching studies and Hammett analysis-support a sensitizer-controlled aerobic photocatalytic pathway involving photoinduced electron transfer and oxygen-mediated catalyst regeneration via superoxide radical anions. This work highlights the efficacy of natural pigments in driving high-efficiency, sustainable organic transformations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.