ArticleLasers in medical science2026
Patient-reported satisfaction and experience of a novel 40.68 MHz radiofrequency therapy: a retrospective real-world study.
Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Radiofrequency (RF) therapy is a well-established non-invasive approach for skin rejuvenation. However, patient-reported outcomes (PROs)- including satisfaction, treatment experience, and tolerability-remain underreported in newer RF devices. This retrospective real-world study aimed to evaluate patient-reported outcomes (PROs) following a single treatment with a novel 40.68 MHz monopolar RF device for facial skin tightening and contouring. We specifically assessed treatment experience, satisfaction drivers, patient-perceived improvement, and tolerability from the patient's perspective. 76 patients who received a single full-face treatment were enrolled in this retrospective, cross-sectional survey study. A structured questionnaire was administered at the 3-month follow-up to assess global aesthetic improvement, domain-specific satisfaction, treatment experience, and tolerability. Physician assessment of standardized photographs at 3 months was also performed as a supportive measure. High overall satisfaction was reported, with 86.84% (95% CI: 77.5% to 92.7%) of patients being "satisfied" or "very satisfied." The greatest improvements were observed in skin tightening/lifting and facial contour, particularly in the jawline (50% (38/76) identified it as the most improved area). The procedure was well-tolerated: 88.16% (67/76, 95% CI: 79.2% to 93.6%) reported intraoperative pain ≤ 3 on a 10-point VAS, 94.74% (72/76, 95% CI: 87.6% to 97.8%) experienced no significant side effects, and 80.26% (61/76) had no or less than 1 day of downtime. Notably, 98.68% (75/76, 95% CI: 93.5% to 99.8%) expressed willingness to undergo repeat treatment. Physician assessment at 3 months also showed improvement in 92.11% (70/76, 95% CI: 83.6% to 96.3%) of patients, similar to the patient-reported improvement rate of 94.74% (72/76). Patients in this real-world study reported high satisfaction, perceived improvement, and good tolerability with the novel 40.68 MHz RF treatment, along with minimal downtime and a strong willingness to repeat treatment. No device-related adverse events were reported by patients in the survey.
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