Evidence map›Paper›PMID 42611142›Full record

ArticleInternational ophthalmology2026

Studying the functional state of the optic nerve in patients with recent onset indirect traumatic optic neuropathy following different treatment modalities.

Mai Abdelnabi Mohammed Elbehwash, Amr Mohammed Mahmoud Elhady, Ahmad Elmasry

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Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mai Abdelnabi Mohammed ElbehwashFaculty of Medicine, Alexandria University, Alexandria, Egypt. mai.abdalnabi@yahoo.com.
Amr Mohammed Mahmoud ElhadyFaculty of Medicine, Alexandria University, Alexandria, Egypt.
Ahmad ElmasryFaculty of Medicine, Alexandria University, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndirect traumatic optic neuropathy (ITON) is a vision‑threatening condition with no universally accepted treatment. This study compares high‑dose steroids, erythropoietin (EPO), and observation.

methodsNinety patients were assigned to three equal groups. BCVA, Ishihara score, visual field MD, and pattern VEP were evaluated.

resultsEPO showed the highest improvement in BCVA, P100 latency, P100 amplitude, color vision, and MD.

conclusionEPO proved superior functional recovery compared with steroids [1, 2, 3] and observation. These findings are promising; however, larger multicenter studies are required to confirm these results.

Indexed as

ErythropoietinEvoked Potentials, VisualGlucocorticoidsOptic NerveOptic Nerve InjuriesVisual AcuityVisual FieldsAdolescentAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedRecovery of FunctionYoung AdultErythropoietinGlucocorticoidsErythropoetin (EPO)Indirect traumatic optic neuropathy (ITON)NeuroprotectionPattern visual evoked potential (PVEP)SteroidsVisual field

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.