Evidence map›Paper›PMID 42611085›Full record

ArticleClinical oral investigations2026

Do bleaching gels supplied in attachable syringes maintain their bleaching efficacy 72 hours after mixing?

Gabrielle Gomes Centenaro, Deisy Cristina Ferreira Cordeiro, Laryssa Mylenna Madruga Barbosa, Michael Willian Favoreto, Tobia Gaston Navarro, Fernanda Vieira Garrido, Alessandro D Loguercio

Abstract read
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabrielle Gomes CentenaroDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil.
Deisy Cristina Ferreira CordeiroDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil.
Laryssa Mylenna Madruga BarbosaDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil.
Michael Willian FavoretoDepartment of Restorative Dentistry, University of São Paulo, São Paulo, SP, Brazil.
Tobia Gaston NavarroDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil.
Fernanda Vieira GarridoDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil.
Alessandro D LoguercioDepartment of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748 Bloco M, Sala 64-A, Uvaranas, Ponta Grossa, PR, 84030-900, Brazil. aloguercio@hotmail.com.ORCID http://orcid.org/0000-0001-9880-4856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate bleaching efficacy (BE), hydrogen peroxide (HP) penetration into the pulp chamber, and selected physicochemical properties (HP concentration, pH, and viscosity) of in-office bleaching agents supplied in attachable syringes from different commercial brands, assessed immediately, after mixing and after 72 h of storage. MATERIALS AND

methods150 human premolars were allocated into fifteen groups (n = 10) according to (1) the commercial brand: DSP 35%, Nano White 35%, SSWhite 35%, Total Blanc 35%, HP Blue 35%, Potenza Bianco 38%, and Opalescence 40%; and (2) storage interval: immediate use or 72 h after mixing. One group stored in artificial saliva served as the negative control (no bleaching). HP concentration at both storage intervals was determined by titration, pH using a digital pH meter, and viscosity by rheometer. BE (ΔE

resultsHP concentration and pH differed among brands and decreased after storage for most gels. All gels produced significantly greater BE than the control (p < 0.05). Storage time had minimal influence on BE. HP diffusion was material-dependent; Viscosity varied among brands, although most gels demonstrated shear-thinning behavior and storage-related changes.

conclusionGels showed material-dependent differences in properties, BE, and PH penetration, with minimal 72-hour storage effects on color. However, storage altered HP concentration, pH, and viscosity in some materials. CLINICAL RELEVANCE: Evaluating gels after 72 h may supports safe reuse, maintaining efficacy while reducing material waste.

Indexed as

Hydrogen PeroxideSyringesTooth BleachingTooth Bleaching AgentsGelsHumansHydrogen-Ion ConcentrationIn Vitro TechniquesMaterials TestingRheologyTime FactorsViscosityGelsHydrogen PeroxideTooth Bleaching AgentsDental Enamel PermeabilityHydrogen PeroxideTooth BleachingTooth permeability

Identifiers

PMID42611085
PMCPMC13486081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.