Evidence map›Paper›PMID 42611080›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Feasibility and safety of same-day discharge after paediatric vagus nerve stimulator implantation for medically intractable epilepsy: a retrospective safety analysis.

Joshua Pepper, Richard Walsh, William B Lo

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Joshua PepperComplex Epilepsy Surgery Service, Birmingham Children's Hospital, Birmingham, UK. joshua.pepper1@nhs.net.
Richard WalshComplex Epilepsy Surgery Service, Birmingham Children's Hospital, Birmingham, UK.
William B LoComplex Epilepsy Surgery Service, Birmingham Children's Hospital, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVagal nerve stimulation (VNS) is an established adjunctive treatment for children with medically intractable epilepsy. It is common practice to admit these children overnight for observation due to concern of airway compromise and other medical complications. We wanted to determine the safety of vagal nerve stimulator insertion in the immediate peri-operative period to determine if same-day discharge is feasible and safe in children.

methodsWe conducted a retrospective review of all paediatric patients (age less than 19 years of age) who underwent vagal nerve stimulator (VNS) implantation at our institution between January 2002 and December 2022.

resultsIn total, 197 patients were included in the analysis. Mean age at surgery was 11.1 years (SD 4.1). Median length of stay was 1 day (IQR 1-1); 21 children (10.7%) were discharged the same day. There were no intraoperative complications. No child (0%) had an immediate postoperative surgical complication. Three children had postoperative medical complications (1.5%), all of which occurred in the first hour after surgery. Developmental delay was present in 95% of documented cases.

conclusionsThese findings support the safety of same-day discharge in appropriately selected patients, with structured criteria and parental guidance.

Indexed as

Ambulatory Surgical ProceduresDrug Resistant EpilepsyPatient DischargeVagus Nerve StimulationAdolescentChildChild, PreschoolFeasibility StudiesFemaleHumansMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeDay case surgeryEpilepsyVagal nerve stimulatorVNS

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.