ArticleJournal of bone and mineral metabolism2026
A DXA-based profile of body composition in celiac patients: a cross-sectional retrospective study.
Article in Journal of bone and mineral metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCeliac disease (CD) is frequently associated with bone and mineral metabolism alterations. As the clinical phenotype shifts from malabsorptive to normal-weight or obese, precise evaluation of body composition is essential to assess metabolic and sarcopenia risks. This study utilized Dual-Energy X-ray Absorptiometry (DXA) to characterize body composition and Bone Mineral Density (BMD) in a contemporary adult CD cohort. MATERIALS AND
methodsWe conducted a single-center, retrospective observational study of 77 CD patients (73% female) under 52 years of age; menopausal women were excluded. DXA was used to measure Appendicular Lean Mass Index (ALMI) Z-score, Bone Mineral Content (BMC) Z-score, and Total BMD Z-score.
resultsSoft tissue parameters, including ALMI and fat mass Z-scores, clustered around zero for both sexes, indicating a composition profile comparable to the NHANES reference population. Conversely, bone health was consistently compromised, especially in women. Female patients exhibited negative Total BMD Z-scores across all age groups, with the lowest mean in the 40-44 age cohort (- 1.0 ± 1.0). BMC Z-scores were also predominantly negative (e.g., - 1.1 ± 1.5 in the 40-44 group). Male patients showed heterogeneous BMD Z-scores, ranging from - 1.04 ± 1.0 (25-29 years) to positive values in older subgroups.
conclusionIn this cohort, the modern CD phenotype presents a preserved soft tissue composition. However, low BMD remains a persistent finding, particularly in premenopausal women. These results underscore the necessity of systematic DXA screening in adult CD patients, regardless of their body mass index or clinical presentation.
Indexed as
Identifiers
42611066What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.