Evidence map›Paper›PMID 42611065›Full record

Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Patterns of negative trauma laparotomy worldwide: a sub-analysis of a global dataset.

William L A Laird, Michael F Bath, Joachim Amoako, Jared Wohlgemut, Carlos M Nuño-Guzmán, Monty Khajanchi, Brandon G Smith, Laura Hobbs, Zane B Perkins, Thomas G Weiser and 3 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

William L A LairdInternational Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0009-0003-9590-3068
Michael F BathInternational Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK. mb2583@cam.ac.uk.ORCID https://orcid.org/0000-0003-1879-1093
Joachim AmoakoUniversity of Ghana Medical School, Accra, Ghana.ORCID http://orcid.org/0000-0001-5734-3926
Jared WohlgemutCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.
Carlos M Nuño-GuzmánHospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, México.
Monty KhajanchiSeth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, India.
Brandon G SmithInternational Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.
Laura HobbsInternational Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.
Zane B PerkinsCentre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0003-4807-8803
Thomas G WeiserDepartment of Surgery, Stanford University, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-3118-3888
Timothy C HardcastleTrauma and Burns Unit, KwaZulu-Natal Department of Health, Inkosi Albert Luthuli Central Hospital, Durban, 4058, South Africa.ORCID http://orcid.org/0000-0002-3967-0234
Tom BashfordInternational Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0228-9779
GOAL-Trauma Collaborative

Funding

Engineering and Physical Sciences Research Council EP/W524633/1 - 2891561Royal College of Surgeons of England Ratanji Dalal Research Fellowship
6 · The paper itself

Abstract

purposeTrauma remains a major contributor to global disability. While the trauma laparotomy can be a life-saving procedure in abdominal injury, a select proportion are performed with no pathology identified intra-operatively, potentially exposing patients to unnecessary morbidity. We aimed to assess the global prevalence of negative laparotomy and identify any influencing factors at both the patient- and system-level.

methodsThis was a secondary analysis of the GOAL-Trauma study, a multicentre prospective international observational study on trauma laparotomy patients, conducted from April to December 2024. We defined a negative laparotomy as where no intra-abdominal injuries were identified during the index operation. A multivariable logistic regression was performed to identify predictive factors for a negative laparotomy.

resultsOf the 1769 patients included, 128 patients (7.2%) underwent a negative laparotomy. Regression analysis demonstrated that a penetrating mechanism of injury (OR 2.37, CI:1.53-3.69, p < 0.001) and a lower grade of surgeon (surgical registrar relative to consultant - OR 2.91, CI:1.90-4.47, p < 0.001) were independent predictors for negative laparotomy. Neither human development index nor hospital resource level impacted negative laparotomy rates.

conclusionOne in every fourteen trauma laparotomies performed in our global cohort was negative, with injury type and surgeon experience having a significant deterministic role. As trauma systems develop globally, recognition in the value of both training and a structured assessment pathway is paramount. The rate of negative trauma laparotomy, either institutionally or regionally, may act as a useful benchmark of trauma system performance and warrants further exploration.

Indexed as

Abdominal InjuriesLaparotomyAdultFemaleGlobal HealthHumansMaleMiddle AgedProspective StudiesWounds, PenetratingGlobal surgeryMorbidityNegative laparotomyTrauma

Identifiers

PMID42611065
PMCPMC13486062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.