Evidence map›Paper›PMID 42611011›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2026

Dissociable Effects of Dysarthria Etiology and Severity on the Minimally Detectable Change of Speech Intelligibility.

Kelly E Zdrowak, Antje S Mefferd, Kaila L Stipancic

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kelly E ZdrowakDepartment of Communicative Disorders and Sciences, University at Buffalo, NY.
Antje S MefferdDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-0595-6717
Kaila L StipancicDepartment of Communicative Disorders and Sciences, University at Buffalo, NY.ORCID 0000-0001-5185-563X

Funding

A taxonomic articulation-focused approach to dysarthria classificationR01DC019648 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Antje Mefferd · 2022 to 2026
$2.3M
Tongue- and Jaw-Specific Contributions to Vowel Acoustic Changes: Towards a Mechanistic Model of Intelligibility Loss and Recovery in DysarthriaR03DC015075 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MEFFERD, ANTJE · 2016 to 2018
$474k
NIDCD NIH HHS R01 DC019648NIDCD NIH HHS R03 DC015075
6 · The paper itself

Abstract

purposeThe minimally detectable change (MDC) provides a threshold for interpreting changes in outcome measures that are outside of measurement error. There is emerging evidence that dysarthria etiology and speech severity impact the MDC of speech intelligibility; however, an investigation of these factors is needed to determine the unique effects of dysarthria etiology and speech severity. The purpose of the current study was to calculate and compare MDCs of speech intelligibility across five dysarthria etiology groups and four severity levels.

methodSpeech Intelligibility Test recordings from 200 speakers were used as stimuli, including recordings from healthy controls (

resultsSpeech severity was a significant predictor of MDCs, with greater impairments to speech intelligibility resulting in higher MDCs. Dysarthria etiology was not a significant predictor of MDCs.

conclusionThe impact of speech severity on MDCs of intelligibility in dysarthria underscores the need to calculate and provide MDCs across severity ranges to enhance the interpretation of patient outcomes.

Indexed as

DysarthriaSpeech IntelligibilityAdultAgedAmyotrophic Lateral SclerosisFemaleHumansHuntington DiseaseMaleMiddle AgedNeurodegenerative DiseasesParkinson DiseaseSeverity of Illness IndexSpeech Production Measurement

Identifiers

PMID42611011
PMCPMC13678543

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.