ArticleBJS open2026
Prognostic importance of tumour deposits with and without concurrent lymph node metastases in patients with stage III colon cancer.
Article in BJS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundTumour deposits (TD) are associated with poor prognosis in patients with colon cancer. However, the current staging system only acknowledges TD in patients without lymph node metastases (LNM). This study investigated the prognostic impact of TD with or without LNM in patients with stage III colon cancer.
methodsThis was a national retrospective cohort study using the Danish Colorectal Cancer Group database, including patients with stage III colon cancer who underwent curative surgery between 2017 and 2022. Patients were stratified into 3 groups: TD alone; LNM alone; and TD and LNM. The primary endpoint was overall survival (OS).
resultsOf the 18 395 patients registered during the study period, 10 241 underwent surgery with curative intent and 9807 had a TD assessment. Of the 3543 stage III CRC patients included, 1091 had TD (30.8%). Of these, 884 had TD and LNM (25.0%), whereas 207 had TD alone (5.8%). Patients with TD and LNM had significantly poorer survival than those with LNM alone (5-year OS 52.2% versus 69.2%; P < 0.001). On subgroup analyses, the presence of TD was associated with poorer OS across all N categories. On multivariable analysis, TD was independently associated with all-cause mortality (hazard ratio 1.25; 95% confidence interval 1.08 to 1.43; P = 0.002). Patients with TD only were significantly less likely to receive adjuvant chemotherapy than those with LNM or TD and LNM (42.5% versus 52.2% and 55.9%, respectively; P = 0.002).
conclusionTD are common in patients with stage III colon cancer and are associated with poorer prognosis across all N categories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.