Evidence map›Paper›PMID 42610698›Full record

ArticlemBio2026

The bacterial pH gradient contributes to persistence in

Hassan E Eldesouky, Kristin N Adams, Justin K Brache, Laarni Kendra T Aguila, Mariana Garcia, Enming Xing, Pui-Kai Li, David R Sherman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hassan E EldesoukyDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-4718-6087
Kristin N AdamsDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Justin K BracheDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Laarni Kendra T AguilaDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-8695-6684
Mariana GarciaDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Enming XingDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
Pui-Kai LiDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
David R ShermanDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-2185-944X

Funding

Seattle Tuberculosis Research Advancement CenterP30AI168034 · NIAID · UNIVERSITY OF WASHINGTON · PI Rhea N Coler, CHETAN SESHADRI · 2022 to 2026
$6.3M
Genetic, Metabolic and Regulatory Control of MIC and Relapse in M. tuberculosisR01AI146194 · NIAID · UNIVERSITY OF WASHINGTON · PI ALLAND, DAVID, SHERMAN, DAVID R · 2020 to 2024
$4.1M
NIAID NIH HHS P30 AI168034NIAID NIH HHS R01 AI146194NIH HHS P30AI168034NIH HHS R01 AI 146194NIH HHS U19 AI 1625598
6 · The paper itself

Abstract

Tuberculosis (TB) remains difficult to cure due in part to poorly defined drug-tolerant persister cells formed by

Indexed as

Antitubercular AgentsMycobacterium tuberculosisProton-Motive ForceDrug Resistance, BacterialDrug ToleranceGene Expression ProfilingHydrogen-Ion ConcentrationMicrobial Sensitivity TestsMicrobial ViabilityNiclosamideAntitubercular AgentsNiclosamidedrug toleranceintracellular pHmembrane potentialniclosamidepersistersPMFTB

Identifiers

PMID42610698
PMCPMC13556226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.