Evidence map›Paper›PMID 42610490›Full record

SynthesisThe Cochrane database of systematic reviews2026

Ketamine and esketamine for postoperative analgesia in gynaecological surgery.

Silvia Marchesi, Jaquette Liljencrantz, Anca Cristina Balintescu, Ioannis Soumpasis, Emma Sinervo, Said Makari, Peter Bentzer, Martin F Bjurström

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia MarchesiDepartment of Clinical Science Malmö, Anesthesiology and Intensive Care, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0003-4791-4507
Jaquette LiljencrantzDepartment of Anesthesiology and Intensive Care, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.
Anca Cristina BalintescuDepartment of Clinical Science and Education, Section of Perioperative and Intensive Care Södersjukhuset, Karolinska Institute, Stockholm, Sweden.
Ioannis SoumpasisDepartment of Clinical Science and Education, Section of Perioperative and Intensive Care, Södersjukhuset, Karolinska Institute, Stockholm, Sweden.
Emma SinervoWomen's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Said MakariDepartment of Obstetrics and Gynecology, Skåne University Hospital, Malmö, Sweden.
Peter BentzerDepartment of Clinical Science Malmö, Anestesiology and Intensive Care, Lund University, Malmö, Sweden.
Martin F BjurströmClinical Pain Research, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis is a protocol for a Cochrane review (intervention). The objectives are as follows: The primary objective of this review is to evaluate the benefits and harms of a subanaesthetic dosage of ketamine/esketamine as an adjunct to perioperative analgesia versus standard analgesia or placebo for reducing postoperative pain in participants undergoing gynaecological surgical procedures. A secondary objective is to assess whether these outcomes differ by type of surgery, background condition, type of drug used (ketamine or esketamine), dosage, and presence of preoperative chronic pain or preoperative long-term or recurrent opioid use.

Indexed as

AnalgesicsGynecologic Surgical ProceduresKetaminePostoperative PainAnalgesiaFemaleHumansRandomized Controlled Trials as TopicAnalgesicsEsketamineKetamine

Identifiers

PMID42610490
PMCPMC13482951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.