ArticleeLife2026
Local inhibitory dynamics underpin temporal integration and functional segregation between barrels and septa in the mouse barrel cortex.
Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
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7 authors.
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Abstract
Mice, like humans, enhance tactile perception through repeated sampling of spatially segregated sensory inputs. In the whisker system, individual whisker identity is preserved along the whisker-brainstem-thalamus-cortex pathway, culminating in distinct cortical domains: barrels and septa. Using simultaneous in vivo recordings from barrel and septal domains, we identify a progressive divergence in spiking activity during repeated single- and multi-whisker stimulation. While the multi- to single-whisker response ratio remains stable in barrels, it increases progressively in septa, suggesting recruitment of local inhibitory circuits. Genetic fate mapping and tissue clearing revealed distinct laminar and regional distributions of SST+ and VIP+ interneurons in barrel and septal domains. Calcium imaging showed that both interneuron types respond to whisker stimulation, but SST+ interneurons were preferentially recruited during repeated multi-whisker stimulation. Deletion of
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