Evidence map›Paper›PMID 42610357›Full record

ArticleAdipocyte2026

Autofluorescence profiles define depot-specific adipocyte phenotypes in perivascular and non-perivascular adipose tissue.

C Javier Rendon, Allison D Redondo-Aguilar, Daniel Vocelle, Matthew P Bernard, D Adam Lauver, Stephanie W Watts, G Andres Contreras

Abstract read
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In one paragraph

Article in Adipocyte, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C Javier RendonDepartment of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-1439-777X
Allison D Redondo-AguilarDepartment of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI, USA.
Daniel VocelleDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-0252-2673
Matthew P BernardDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-5950-3580
D Adam LauverDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-2752-1124
Stephanie W WattsDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-9653-6357
G Andres ContrerasDepartment of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-4969-2178

Funding

The perivascular adipocyte: integrating mechanical and structural cues into vasoactive functionP01HL152951 · NHLBI · MICHIGAN STATE UNIVERSITY · PI Stephanie W Watts · 2022 to 2026
$13.3M
NHLBI NIH HHS P01 HL152951
6 · The paper itself

Abstract

Perivascular adipose tissue (PVAT) is recognized as the functional fourth layer of the vasculature. Unlike non-PVAT depots, PVAT is continuously exposed to haemodynamic forces, potentially altering the morphometry of its adipocytes. While transcriptomics studies have identified diverse adipocyte populations, characterizing these cells remains difficult because their inherent fragility limits standard antibody-based phenotyping. Autofluorescence has emerged as a label-free alternative for characterizing cellular heterogeneity. However, autofluorescence-based characterization of PVAT adipocytes remains unexplored, and it is unknown if these cells exhibit distinct profiles reflecting their specific anatomical location. This study aimed to define the autofluorescence profiles of PVAT and non-PVAT adipocytes. Using Sprague-Dawley rats (

Indexed as

AdipocytesAdipose TissueAnimalsMalePhenotypeRatsRats, Sprague-DawleyAdipocytesadiposeautofluorescenceflow cytometryPVAT

Identifiers

PMID42610357
PMCPMC13488464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.