ArticleCanadian respiratory journal2026
Association Between Pulmonary Function Parameters and Apnea Hypopnea Index in Asthmatic Children Living at High Altitude.
Article in Canadian respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association Between Pulmonary Function Parameters and Apnea Hypopnea Index in Asthmatic Children Living at High Altitude.Canadian respiratory journal · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObstructive sleep apnea (OSA) has been associated with poorer asthma outcomes in children, including reduced disease control and a greater risk of exacerbation. However, little is known about the relationship between sleep-disordered breathing severity and pulmonary function in pediatric patients residing at high altitude.
methodsWe conducted a cross-sectional study including children aged 3-12 years with physician-diagnosed asthma who underwent overnight polysomnography at a referral center in Bogotá, Colombia (2640 m above sea level), between 2012 and 2017. Clinical characteristics, spirometric measurements, oscillometry parameters, and polysomnographic variables were collected and analyzed. Associations between pulmonary function indices and apnea-hypopnea measures were evaluated using Spearman correlation analysis.
resultsSixty-four children were included, of whom 59.4% had moderate-to-severe asthma and 59.4% had uncontrolled disease. In oscillometry, airway resistance at 5 Hz (R5) demonstrated an inverse correlation with AHI before bronchodilator administration (r = -0.440, p < 0.05) and after bronchodilator administration (r = -0.491, p < 0.05). Similar inverse correlations were observed between R5 and OAHI. Among spirometric variables, postbronchodilator FEV1 was negatively correlated with OAHI (r = -0.329, p < 0.05). No significant associations were found between OSA severity and asthma severity, body mass index, or nocturnal oxygen saturation.
conclusionsOur findings revealed an association between the AHI and VEF1 in asthmatic children residing in a tropical city at high altitude. However, the results regarding the relationship between AHI and R5 were contradictory.
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