Evidence map›Paper›PMID 42610258›Full record

ArticleJournal of separation science2026

Aerogel Pore-Confined High-Loading MOF-199 for Micro-Solid-Phase Extraction of Methorphan Enantiomer in Biological Samples.

Shaojing Huang, Suling Zhang, Huanhuan Yao, Zhiwei Huang, Dong Zhang, Ying Pan, Ting Lü, Hongting Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of separation science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shaojing HuangCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.
Suling ZhangCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.
Huanhuan YaoInstitute of Criminal Science and Technology, Public Security Bureau of Hangzhou, Hangzhou, China.
Zhiwei HuangNingbo Huan Yu Environmental Engineering Consult Company, Ningbo, China.
Dong ZhangCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.
Ying PanCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.
Ting LüCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.
Hongting ZhaoCollege of Materials & Environmental Engineering, Hangzhou Dianzi University, Hangzhou, China.

Funding

Zhejiang Province Public Welfare Technology Application Research Project LGC21B050003
6 · The paper itself

Abstract

Dextromethorphan is a widely used clinical antitussive, while its enantiomer, levomethorphan, is a controlled substance. Chiral separation and trace detection of the two enantiomers in biological samples are critically important. Herein, a micro-solid-phase extraction method coupled with enantioselective ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) was proposed for the analysis of methorphan enantiomers. MOF-199/cellulose aerogel spheres fabricated via a facile in situ growth strategy were employed as the sorbent. By immersing Cu

Indexed as

DextromethorphanMetal-Organic FrameworksSolid Phase MicroextractionAerogelsCelluloseChromatography, High Pressure LiquidHumansParticle SizePorositySolid Phase ExtractionStereoisomerismAerogelsCelluloseDextromethorphanMetal-Organic FrameworksaerogelLC–MSmetal–organic frameworkmethorphansolid‐phase extraction

Identifiers

PMID42610258
PMCPMC13482712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.