ArticleJournal of asthma and allergy2026
Vitamin D Deficiency in Children with Asthma and Overweight/Obesity in Qatar.
Article in Journal of asthma and allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Childhood asthma, obesity, and vitamin D deficiency are all highly prevalent in Qatar, and children with concurrent asthma and obesity experience greater disease severity and poorer treatment response than those with asthma alone. Although vitamin D deficiency has been linked to asthma, the combined effect of co-existing asthma and overweight/obesity on vitamin D status has not been characterized in this population, warranting further investigation. Methods: This cross-sectional observational study assessed serum 25-hydroxyvitamin D levels in children aged 6-17 years, residing in Qatar. A total of 364 children were divided into four groups: children with normal weight and asthma (NW-A), children with overweight/obesity and asthma (OO-A), children with overweight/obesity and no asthma (OO), and children with normal weight and no asthma (NW). Between-group differences were assessed using chi-square, Dunn (Bonferroni-corrected), and Spearman correlation tests, and a multivariable logistic regression model adjusted for age, sex, BMI, and atopy was used to examine the association between asthma and vitamin D status. Results: Children in all the four groups demonstrated a high prevalence of vitamin D deficiency (<50 nmol/L), regardless of asthma or BMI. Vitamin D deficiency was present in 81.1% of OO, 73.9% OO-A, 68.3% of NW, and 66.3% of NW-A, with no statistically significant difference across groups. Vitamin D levels were similar between NW-A and OO-A, but OO group had significantly lower levels. A negative correlation between BMI and vitamin D levels was observed in OO-A ( Conclusion: Higher BMI was associated with lower serum vitamin D levels in overweight/obese children, independent of asthma status, whereas asthma was not independently associated with vitamin D deficiency. Given the cross-sectional design, these findings indicate associations rather than causal relationships. The high prevalence of vitamin D deficiency across all study groups highlights a substantial public-health concern and supports the value of routine screening, nutritional and lifestyle measures, and where indicated, vitamin D supplementation, in pediatric health management in Qatar, pending confirmation from longitudinal and interventional studies.
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