Evidence map›Paper›PMID 42610031›Full record

ArticleCureus2026

Investigating Intracerebral Hemorrhage Evacuation Procedure Volumes Before and After the Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation III (MISTIE III) Trial.

Graham A Branscom, Evan M Ren, Keshv Krishna Srinivasan, Michael B Lemonick, Matthew T Carr, Leilei Hao, Akhil Rao, Tanvir F Choudhri, Christopher P Kellner, John Y K Lee

Abstract read
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In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Graham A BranscomNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Evan M RenNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Keshv Krishna SrinivasanNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Michael B LemonickNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Matthew T CarrNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Leilei HaoNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Akhil RaoNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Tanvir F ChoudhriNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
Christopher P KellnerNeurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA.
John Y K LeeNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Intracerebral hemorrhage (ICH) constitutes 10-15% of all strokes in the United States and has a 30-40% mortality rate. The Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation III (MISTIE III) trial showed no significant functional benefit of minimally invasive catheter drainage (MICD) and postoperative thrombolysis compared to medical management. Our objective is to evaluate how the results of the MISTIE III trial corresponded to changes in ICH evacuation procedure volumes. Materials and methods We used an aggregated dataset containing Medicare Part B procedure data from 2013 to 2023. We calculated the normalized volume of MICD procedures, supratentorial craniotomies, and infratentorial craniotomies for ICH evacuation. We normalized the volumes by calculating the percentage of all neurosurgical procedures that included ICH evacuation for each year. We used an interrupted time series (ITS) to find statistically significant changes in volumes before (β

Indexed as

hemorrhagic strokeintracerebral hemorrhagemedical insuranceminimally invasive surgeryrandomized controlled trial

Identifiers

PMID42610031
PMCPMC13480301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.