Evidence map›Paper›PMID 42609842›Full record

ArticleOTO open

The T Stage of Papillary Thyroid Cancer and Its Effect on Regional Complications of Thyroidectomy.

Fahad Rind, Songzhu Zhao, Stephen Kang, Catherine T Haring, Amit Agrawal, Enver Ozer, Matthew O Old, Ricardo L Carrau, Nolan B Seim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fahad RindDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0003-3366-886X
Songzhu ZhaoDepartment of Otolaryngology-Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA.ORCID https://orcid.org/0009-0007-9773-6530
Stephen KangDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0002-0865-6149
Catherine T HaringDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0002-9317-6536
Amit AgrawalDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0003-4047-5708
Enver OzerDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0002-3816-4196
Matthew O OldDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0003-1795-5877
Ricardo L CarrauDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0003-3867-2032
Nolan B SeimDivision of Head and Neck Oncology Ohio State University Comprehensive Cancer Center, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Columbus Ohio USA.ORCID https://orcid.org/0000-0002-9227-5313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the impact of increasing AJCC T stage on postoperative morbidity in patients undergoing thyroidectomy for papillary thyroid cancer. Study Design: Retrospective cross-sectional database study. Setting: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP), which collects surgical outcomes data from ~700 US hospitals. Methods: NSQIP Participant User Files were queried for thyroidectomy procedures (CPT codes 60210, 60212, 60220, 60225, 60240, 60252, 60254, 60260) from 2016 to 2020 with a pathology-confirmed diagnosis of papillary thyroid cancer. Primary exposure was T stage and outcomes included hoarseness, hypocalcemia, and hematoma formation. Multivariate analysis controlled for N stage, total thyroidectomy, multifocality, and neck dissection. Results: A total of 10,901 cases were identified (74.2% female; mean age 50.1 ± 15.1 years). Compared to early-stage tumors, T3 cancers were associated with increased risk of hoarseness (OR 1.614, 95% CI 1.260-2.074, Conclusion: Increasing T stage is associated with significantly higher postoperative morbidity in patients with papillary thyroid cancer, particularly when advancing to T3 or T4. These findings highlight the importance of preoperative risk assessment and surgical planning in advanced disease.

Indexed as

papillary thyroid cancersurgerythyroid cancerT stage

Identifiers

PMID42609842
PMCPMC13479466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.