ArticleCJC open2026
Socioeconomic Burden of Pulmonary Arterial Hypertension in Patients and Caregivers: A Canadian Cross-Sectional Study.
Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
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Abstract
Background: Pulmonary arterial hypertension (PAH) is a serious condition that can impair daily functioning, employment, and quality of life for working-age individuals. We evaluated the real-world socioeconomic burden of PAH on patients and their caregivers. Methods: We conducted a cross-sectional survey of adult Canadian patients between August15, 2023 and October 9, 2023. Using the Work Productivity and Activity Impairment Questionnaire, the EQ-5D Visual Analogue Scale, and additional survey items, we assessed employment status, work limitations, changes in work patterns, quality of life, and perceived caregiver burden. Predictors of employment were identified using multivariate logistic regression. Results: Among 217 participants, 61 (28%) were employed. Working participants reported high presenteeism-that is, impairment while working, due to PAH (50%, interquartile range [IQR] 10, 70). Older age (odds ratio [OR] 0.62, 95% confidence interval [CI] 0.54-0.72, Conclusions: PAH imposes a substantial socioeconomic burden on patients and caregivers. Patients with PAH experience low rates of employment, high presenteeism, and significant caregiver work loss. These findings highlight an underrecognized aspect of PAH care.
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