Evidence map›Paper›PMID 42609729›Full record

ArticleJournal of parasitology research2026

Effects of Astragaloside IV Combined With Metronidazole on Cyst Shedding and Mucosal Immune and Inflammatory Responses in a Murine Model of Giardiasis.

Hossein Mahmoudvand, Amal Khudair Khalaf, Sahar Mahmoudvand, Ahmad Adineh, Aram Oladi, Javad Ghasemian Yadegari

Abstract read
In one paragraph

Article in Journal of parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran, lums.ac.ir.ORCID https://orcid.org/0000-0003-4194-393X
Amal Khudair KhalafDepartment of Microbiology, College of Medicine, University of Thi-qar, Thi-qar, Iraq, utq.edu.iq.ORCID https://orcid.org/0009-0004-7915-5503
Sahar MahmoudvandDepartment of Toxicology, Lorestan University of Medical Sciences, Khorramabad, Iran, lums.ac.ir.ORCID https://orcid.org/0009-0002-5453-9741
Ahmad AdinehDepartment of Toxicology, Lorestan University of Medical Sciences, Khorramabad, Iran, lums.ac.ir.ORCID https://orcid.org/0000-0003-4920-7857
Aram OladiDepartment of Pharmacognosy, Lorestan University of Medical Sciences, Khorramabad, Iran, lums.ac.ir.ORCID https://orcid.org/0009-0009-6521-3633
Javad Ghasemian YadegariDepartment of Pharmacognosy, Lorestan University of Medical Sciences, Khorramabad, Iran, lums.ac.ir.ORCID https://orcid.org/0009-0004-6505-0719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Giardiasis continues to be a significant intestinal parasitic infection, with instances of treatment failure and recurrence underscoring the necessity for supplementary therapeutic approaches. Astragaloside (AGS), a bioactive compound known for its anti-inflammatory and immunomodulatory effects, may serve as a promising adjunctive treatment; however, its efficacy against Methods: The MTT colorimetric assay was used to evaluate the in vitro antigiardial effects of AGS against Results: AGS exhibited a clear concentration-dependent inhibitory effect on the viability of Conclusion: AGS administration was associated with a reduced

Indexed as

giardiasisinflammationin vivonatural productstreatment

Identifiers

PMID42609729
PMCPMC13479967

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.