Observational studyFrontiers in public health2026
Current status and influencing factors of early delayed neurocognitive recovery in older adult patients after major orthopedic surgery under general anesthesia: a cohort study.
Observational study in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the current status of early delayed neurocognitive recovery (dNCR) in older adult patients after major orthopedic surgery in China and analyze its influencing factors, providing a reference for early intervention by clinical workers. Design: Observational cohort study. Methods: A convenience sampling method was used to select patients aged 60 years or older who underwent major orthopedic surgery under general anesthesia at a tertiary hospital in Qingdao, Shandong Province, from September 2025 to June 2026. A general information questionnaire, depression scale, frailty scale, nutrition scale, and sleep quality scale were used to collect data 1 day before surgery. The Beijing version of the Montreal Cognitive Assessment (MoCA) was administered 1 day before surgery and on postoperative day 7 or before discharge (whichever occurred first). Variables with Results: A total of 505 patients were included, of whom 155 (30.69%) developed dNCR. Regression analysis showed that age, sleep disorder, anesthesia time, and stroke history were independent risk factors for postoperative dNCR, and the MoCA score was a protective factor ( Conclusion: After major orthopedic surgery, dNCR is relatively common in older adult patients. Clinical workers should strengthen early preoperative screening, identify high-risk patients, and provide targeted interventions and cognitive training, so as to improve patient outcomes.
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