Evidence map›Paper›PMID 42609522›Full record

ArticleMedComm2026

Restricted TCR Diversity and Expansion of CD177

Yawen Xie, Xunyao Wu, Guoyu Zhao, Xianli Lei, Jiahui Zhang, Na Cui, Bin Du

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yawen XieDepartment of Critical Care Medicine Beijing Chao-Yang Hospital Capital Medical University Beijing China.
Xunyao WuState Key Laboratory of Complex Severe and Rare Diseases Clinical and Science Investigation Institute Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China.
Guoyu ZhaoDepartment of Critical Care Medicine Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China.
Xianli LeiDepartment of Critical Care Medicine Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China.
Jiahui ZhangDepartment of Critical Care Medicine Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China.
Na CuiDepartment of Critical Care Medicine Beijing Chao-Yang Hospital Capital Medical University Beijing China.
Bin DuState Key Laboratory of Complex Severe and Rare Diseases Clinical and Science Investigation Institute Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College Beijing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced immunosuppression contributes to poor outcomes in sepsis patients, yet the mechanisms underlying T cell dysfunction remain incompletely understood. We integrated single-cell RNA sequencing (scRNA-seq), paired single-cell T cell receptor sequencing (scTCR-seq), bulk RNA sequencing (RNA-seq), and flow cytometry to characterize CD8

Indexed as

CD4+ TCD8+ Tseptic shock‐associated immunosuppressionsingle‐cell RNA sequencing (scRNA‐seq)single‐cell T cell receptor sequencing (scTCR‐seq)

Identifiers

PMID42609522
PMCPMC13478844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.