Evidence map›Paper›PMID 42609510›Full record

ArticleCase reports in cardiology2026

Classic Murmur, Unexpected Diagnosis: A Case Report and Pathophysiological Review.

José Maria Gonçalves Fernandes, Flávio Bonaparte Laranjeira, Margareth de Souza Lira Handro, Benício de Oliveira Romão, Francisco de Assis Costa, Ivan Romero Rivera, Maria Alayde Mendonça Rivera

Abstract read
In one paragraph

Article in Case reports in cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

José Maria Gonçalves FernandesDepartment of Cardiology, Faculty of Medicine, Federal University of Alagoas, Maceió, Alagoas, Brazil, ufal.edu.br.ORCID https://orcid.org/0000-0002-4984-3995
Flávio Bonaparte LaranjeiraFaculty of Medicine, Federal University of Alagoas, Maceió, Alagoas, Brazil, ufal.edu.br.ORCID https://orcid.org/0009-0007-2757-8370
Margareth de Souza Lira HandroDivision of Cardiology, Harmonycor-Harmony Medical Center, Maceió, Alagoas, Brazil.ORCID https://orcid.org/0009-0002-6264-6168
Benício de Oliveira RomãoDivision of Cardiology, Unicar-Unidade Cardiológica de Alagoas, Arapiraca, Alagoas, Brazil.ORCID https://orcid.org/0009-0009-7901-896X
Francisco de Assis CostaDepartment of Cardiology, Faculty of Medicine, Federal University of Alagoas, Maceió, Alagoas, Brazil, ufal.edu.br.ORCID https://orcid.org/0000-0003-2101-1684
Ivan Romero RiveraDepartment of Cardiology, Faculty of Medicine, Federal University of Alagoas, Maceió, Alagoas, Brazil, ufal.edu.br.ORCID https://orcid.org/0000-0001-9473-132X
Maria Alayde Mendonça RiveraDepartment of Cardiology, Faculty of Medicine, Federal University of Alagoas, Maceió, Alagoas, Brazil, ufal.edu.br.ORCID https://orcid.org/0000-0003-3322-0459

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systolic murmur best heard at the aortic area with radiation to the neck is considered a hallmark of aortic stenosis. We report a patient with this auscultatory pattern in whom investigation revealed an unexpected diagnosis. Accompanying symptoms reinforced the initial suspicion, adding another layer of complexity to the diagnostic process. This case highlights the limitations of relying solely on symptom profile and murmur topography, and underscores the importance of comprehensive physical examination and diagnostic imaging in evaluating valvular heart disease.

Indexed as

aortic stenosiscardiac auscultationheart murmursmisdiagnosis

Identifiers

PMID42609510
PMCPMC13478730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.