Evidence map›Paper›PMID 42609472›Full record

ArticleCase reports in cardiology2026

Rare Cause of Restrictive Cardiomyopathy: A Case Report of Löffler Endocarditis.

Jose L Diz Ferre, Edward G Soltesz, Agostina Fava

Abstract read
In one paragraph

Article in Case reports in cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jose L Diz FerreKaufman Center for Heart Failure, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0009-0000-4967-3781
Edward G SolteszKaufman Center for Heart Failure, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0002-1231-8329
Agostina FavaSection of Regional Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0002-8565-2811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Löffler endocarditis, an idiopathic hypereosinophilic syndrome, can present symptoms of heart failure and peripheral eosinophilia. We present the case of a 46-year-old woman with fatigue, shortness of breath, and edema, who was found to have thrombocytopenia, elevated cardiac biomarkers, and hypereosinophilia (2.96 k/uL). Cardiac MRI revealed hypertrophic cardiomyopathy, right ventricular hypertrophy, and a restrictive filling pattern, raising suspicion for Löffler endocarditis. Despite initial corticosteroid and diuretic treatment, she was readmitted with persistent symptoms. This case highlights the diagnostic imaging and treatment challenges with corticosteroid therapy, to control eosinophilic infiltration and prevent irreversible cardiac damage. Löffler endocarditis should be considered in the imaging differential diagnosis of unexplained heart failure.

Identifiers

PMID42609472
PMCPMC13478794

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.