ArticleFrontiers in neuroscience2026
Reactive-accelerated-aging soak testing of thin-film polyimide layers treated with an oxygen plasma and chemical soaking.
Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Reliable bonding between polyimide layers is critical for the long-term performance of thin-film neural interfaces, yet the long-term durability of common adhesion methods under physiologically relevant conditions remains unclear. This study uses reactive-accelerated-aging (RAA) soak testing at 87°C to compare the ability of surface treatments based on oxygen plasma and KOH/HCl soaks to enhance polyimide-to-polyimide adhesion. Peel testing was performed as a function of soak time and strip width to quantify degradation behavior. Oxygen plasma-treated samples exhibited high initial adhesion (~262 mN/mm) but degraded rapidly in RAA, with bond strength decreasing linearly and failing within 3 to 6 days depending on width. The width dependence indicates edge-driven degradation, for which a predictive model of adhesion loss was developed. In contrast, KOH/HCl-treated samples showed lower initial adhesion strength (~150 mN/mm) but minimal degradation over the test duration and corresponded to an estimated minimum 40-fold improvement in bond lifetime. These overall results from this study demonstrate that plasma-based bonding of polyimide films is highly susceptible to oxidative degradation, while chemically reconstituted interfaces provide significantly improved stability that could be beneficial for chronic neural-implant applications.
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