Evidence map›Paper›PMID 42609362›Full record

ArticleFrontiers in medicine2026

Case Report: Opioid-sparing general anesthesia with bilateral quadratus lumborum block for cesarean delivery in a parturient with spinal deformity.

Shuanjun Zhang, Juxian Zhao, Fang Yang, Cuiwen Li, Haixia Wei, Wen Li, Zhonghua Bai, Huiwen Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shuanjun Zhang *Department of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Juxian Zhao *Department of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Fang YangDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Cuiwen LiDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Haixia WeiDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Wen LiDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Zhonghua BaiDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.
Huiwen WangDepartment of High Altitude Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For parturients with contraindications to neuraxial anesthesia, GA remains the primary alternative. However, conventional opioid-based GA may increase the risk of adverse neonatal outcomes. Therefore, exploring opioid-sparing GA combined with bilateral QLB is of considerable clinical value for reducing potential maternal and neonatal risks.In the present case, the patient was a 35-year-old full-term parturient with spinal deformity who declined neuraxial anesthesia, constituting a contraindication to such techniques.During cesarean delivery, we successfully implemented an opioid-sparing GA regimen combined with bilateral QLB. The essential components of GA-hypnosis, analgesia, muscle relaxation, and attenuation of the stress response-were achieved through a multimodal approach. The anesthetic management was carefully designed following a comprehensive preoperative evaluation and a thorough analysis of the challenges associated with conventional opioid-based GA in this patient. Multidisciplinary collaboration and meticulous perioperative planning were emphasized throughout the peripartum period. This anesthetic approach effectively integrated the advantages of regional nerve block and GA. Notably, the neonate exhibited no signs of opioid-related respiratory depression, with no occurrence of low Apgar scores, and no resuscitative interventions were required after delivery. This case highlights a novel opioid-sparing strategy for cesarean delivery under GA.

Indexed as

bilateral quadratus lumborum blockcase reportcesarean deliveryopioid-sparing general anesthesiaspinal deformity

Identifiers

PMID42609362
PMCPMC13478083

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