ArticleFrontiers in medicine2026
Association between low-density lipoprotein cholesterol and the risk of bronchial asthma: a case-control study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the association between low-density lipoprotein cholesterol (LDL-C) and the risk of bronchial asthma. A retrospective case-control study was conducted, including 944 patients with asthma and 1,580 controls. Subjects were divided by median LDL-C into high and low groups. Propensity score matching (PSM 1:1) was performed for age, gender, body mass index (BMI), family history, smoking, alcohol use, and diabetes, yielding 1,043 participants in each LDL-C group. Multivariate binary logistic regression was used post-PSM to assess the independent association between LDL-C and asthma risk. Stratified and interaction analyses were performed by age, gender, and BMI. Restricted cubic splines (RCS) with logistic regression were used to evaluate non-linear relationships and identify exploratory turning points. After PSM, multivariate analysis indicated LDL-C was independently associated with asthma risk (OR: 1.75, 95% CI: 1.47-2.09). Stratified analysis showed LDL-C was significantly associated with asthma risk in individuals aged <60 years (OR: 2.61, 95% CI: 2.04-3.36) but not in those ≥60 years (OR: 1.16, 95% CI: 0.91-1.49). Interaction analysis confirmed a significant difference between age strata (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.