Evidence map›Paper›PMID 42609306›Full record

ArticleFrontiers in cellular and infection microbiology2026

Tldi1 deficiency mediates Tlde1 self-toxic effect to regulate the adaptability of

Junfeng Zhang, Chang Liu, Songbiao Chen, Rongxian Guo, Yanyan Jia, Jing Li, Chengshui Liao, Ke Ding, Lei He, Ke Shang

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Junfeng Zhang *College of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
Chang Liu *College of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Songbiao ChenCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Rongxian GuoCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Yanyan JiaCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Jing LiCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Chengshui LiaoCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Ke DingCollege of Animal Science and Technology, Henan Institute of Science and Technology, Xinxiang, China.
Lei HeCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.
Ke ShangCollege of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology;, Luoyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Type VI secretion system (T6SS) is a key bacterial secretion device in Methods: Firstly, molecular bioinformatics approaches were employed to analyze the physicochemical properties, hydrophilicity, hydrophobicity, transmembrane regions, subcellular localization, as well as secondary and tertiary structures of the Tldi1 protein. Secondly, a Results: The results showed that compared with the wild-type (WT) strain, the Δ Discussion: Tldi1, as a key immunity protein for Tlde1 neutralization, indirectly regulates the environmental adaptability and host immune homeostasis of

Indexed as

Bacterial ProteinsBacterial ToxinsHost-Pathogen InteractionsSalmonella InfectionsSalmonella typhimuriumType VI Secretion SystemsAnimalsDisease Models, AnimalMiceBacterial ProteinsBacterial ToxinsType VI Secretion Systemsenvironmental stress adaptationhost-pathogen interactionsSalmonella TyphimuriumT6SSTldi1

Identifiers

PMID42609306
PMCPMC13478106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.