ArticleFrontiers in public health2026
The association between treatment burden and quality of life in older adults with multimorbidity: the mediating role of personal mastery and the moderating role of social support-a cross-sectional study in China.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Treatment burden is associated with health-related quality of life (HRQoL) in multimorbidity, but its psychological and social correlates in older adults remain unclear. This study examined whether personal mastery was statistically linked to the association between treatment burden and HRQoL and whether social support moderated the association between treatment burden and personal mastery. Methods: A cross-sectional survey was conducted among 470 outpatients aged 60 years and older with multimorbidity in Jiangsu Province, China. Treatment burden, personal mastery, social support, and HRQoL were assessed using validated scales. Pearson correlations and PROCESS Model 7 with 5,000 bootstrap resamples were used, adjusting for age, BMI, sex, income, and education. Results: Treatment burden was negatively associated with personal mastery ( Conclusion: Greater treatment burden was associated with poorer physical HRQoL and showed negative indirect associations with physical and mental HRQoL through lower personal mastery. These indirect associations were weaker at higher social support.
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