Evidence map›Paper›PMID 42609265›Full record

ArticleFrontiers in physiology2026

Duration-dependent effects of dry cupping on autonomic modulation and trapezius tissue compliance in smartphone users: a dose-finding study.

Chien-Liang Chen, Ioannis Manousakas, Jing-Shia Tang

Abstract read
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Chien-Liang ChenDepartment of Physical Therapy, I-Shou University, Kaohsiung, Taiwan.
Ioannis ManousakasDepartment of Biomedical Engineering, I-Shou University, Kaohsiung, Taiwan.
Jing-Shia TangDepartment of Nursing, Chung-Hwa University of Medical Technology, Tainan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prolonged smartphone use is associated with forward head posture, increased trapezius stiffness, and altered autonomic nervous system regulation. Dry cupping applies localized negative pressure-mediated mechanical stimulation that may influence myofascial properties and autonomic activity; however, its interactive effects of pressure and duration remain unclear. This study investigated the effects of different pressure and duration combinations of dry cupping on autonomic modulation indexed by heart rate variability (HRV) and trapezius tissue compliance in smartphone users. Methods: Thirty-two university students were classified into the smartphone addiction and control groups. A counterbalanced crossover design was implemented, in which each participant received four cupping protocols: -300 mmHg or -450 mmHg applied for 5 or 15 min. HRV, trapezius soft tissue compliance measured using a real-time monitoring system, and functional questionnaires were assessed before and after each intervention. Results: HRV spectral indices indicated reduced sympathetic activity and did not reach statistical significance for parasympathetic activity (p=0.062) following cupping. Compared to 5-min sessions, 15-min protocols significantly increased total power as well as both low- and high-frequency components. Trapezius tissue compliance showed the highest improvement after -300 mmHg applied for 15 min. Functional disability scores remained unchanged. Conclusion: In this subclinical population, dry cupping modulated autonomic activity and improved trapezius tissue compliance in a duration-dependent manner, with 15-minute applications generally producing greater effects than 5-minute applications. Treatment duration exerted a greater influence than pressure intensity, with moderate pressure sustained for 15 min producing the most pronounced autonomic and biomechanical responses.

Indexed as

autonomic modulationdry cuppingheart rate variabilitypressure-duration effectstissue compliancetrapezius muscle

Identifiers

PMID42609265
PMCPMC13477954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.