Evidence map›Paper›PMID 42609262›Full record

ArticleFrontiers in public health2026

Predictors of childhood vaccination and recent influenza vaccination in older Brazilian adults: an analysis using conventional regression and machine learning approaches.

Xianglong Xu, Biying Wang, Kubra Maqsood Memon, Chen Sun, Yang Cheng, Fuquan Long

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Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xianglong XuDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Biying WangSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Kubra Maqsood MemonSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chen SunSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yang ChengSchool of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fuquan LongDepartment of Sexually Transmitted Disease, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vaccination is an important public health intervention across the life course but its determinants may differ by life stage. We aimed to identify and compare predictors of childhood vaccination and recent influenza vaccination among older adults using conventional and machine learning approaches. Methods: We used data from the second wave (2019-2021) of the Brazilian Longitudinal Study of Aging (ELSI-Brazil), a nationally representative cohort of individuals aged 50+. Analyses included 9,211 participants for childhood vaccination and 9,863 for influenza vaccination. Predictors were selected from sociodemographic, environmental, lifestyle, and health domains. Multivariable logistic regression and machine learning algorithms were used, with performance evaluated via area under the receiver operating characteristic curve (AUC). Results: The best-performing machine learning model demonstrated acceptable performance for childhood vaccination (AUC = 0.72, 95% CI: 0.69-0.74) and recent influenza vaccination (AUC = 0.67, 95% CI: 0.64-0.70). For childhood vaccination, both analytical approaches identified age, sex, rural residence, parental education, school attendance at age 10, childhood access to books, and allergy as important predictors. Machine learning additionally identified age at school initiation, childhood economic status, self-rated childhood health, severe diarrhea, and history of childhood infectious diseases. Key predictors for recent influenza vaccination included age, marriage, educational level, employment, and hypertension/diabetes. Machine learning additionally highlighted the importance of vaccination history during childhood, life satisfaction, BMI, and mental health. Conclusion: Early-life socioeconomic and health conditions are important predictors of childhood immunization history, whereas current sociodemographic and health status are key predictors of recent vaccination. Machine learning identified supplementary predictors beyond traditional methods.

Indexed as

Influenza, HumanInfluenza VaccinesMachine LearningVaccinationAgedBrazilFemaleHumansLongitudinal StudiesMaleMiddle AgedPrediction AlgorithmsPredictive Learning ModelsSocioeconomic FactorsInfluenza Vaccineschildhoodinfluenzamachine learningolder adultspredictorsrecent vaccinationvaccination

Identifiers

PMID42609262
PMCPMC13477924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.