ArticleFrontiers in physiology2026
Exercise-induced pulse pressure augmentation is positively associated with exercise capacity in patients after transcatheter aortic valve implantation.
Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Although transcatheter aortic valve implantation (TAVI) improves outcomes in elderly patients with aortic stenosis, many continue to have reduced exercise capacity. While higher resting pulse pressure (PP) has been linked to worse prognosis, the impact of exercise-induced PP changes remains unclear. This study examined the association between PP change (ΔPP) during exercise and exercise capacity after TAVI.
methodsThis single-center retrospective study included patients who underwent transfemoral TAVI at the Sakakibara Heart Institute between 2014 and 2024 and subsequently participated in outpatient cardiac rehabilitation. ΔPP was defined as the difference in PP between rest and peak oxygen uptake (peak VO
resultsA total of 71 patients were analyzed (median age 82 years (range 70-92), 46% women). The High ΔPP group (ΔPP > 47 mmHg, n = 35) showed significantly higher peak VO
conclusionsIn this single-center retrospective cohort, greater exercise-induced ΔPP was associated with higher peak VO
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