Evidence map›Paper›PMID 42609232›Full record

ArticleFrontiers in neurology2026

SPRIN

Jiao Ye, Yan Wan, Yifan Zhou, Qinghui Xiao, Qingcan Li, Wenyong Gao, Jichuan Hu, Ming Huang, Bo Hu, Huijuan Jin

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiao Ye *Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yan Wan *Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yifan Zhou *Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qinghui XiaoDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qingcan LiDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wenyong GaoDepartment of Neurology, Wuhan Hankou Hospital, Wuhan, China.
Jichuan HuDepartment of Neurology, People's Hospital of Dongxihu District, Wuhan, China.
Ming HuangDepartment of Neurology, Hubei Provincial Hospital of Integrated Chinese and Western Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Bo HuDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huijuan JinDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to construct and validate a nomogram for the intuitive prediction of 90-day unfavorable outcomes in patients with minor ischemic stroke who underwent intravenous thrombolysis. Methods: Data were extracted from the Multicenter Clinical Trial of Revascularization Treatment for Acute Ischemic Stroke (TRAIS) study. Multivariable logistic regression was used to identify independent factors associated with 90-day unfavorable outcomes (modified Rankin Scale [mRS] score 2-6) in patients with minor ischemic stroke (National Institutes of Health Stroke Scale [NIHSS] score 0-5) receiving intravenous thrombolysis. A nomogram (designated as SPRIN Results: A total of 1,438 eligible patients were enrolled and randomly assigned to a derivation cohort ( Conclusion: The SPRIN

Indexed as

Fibrinolytic AgentsIschemic StrokeNomogramsThrombolytic TherapyAgedFemaleHumansMaleMiddle AgedPrognosisTissue Plasminogen ActivatorTreatment OutcomeFibrinolytic AgentsTissue Plasminogen Activatorintravenous thrombolysisminor ischemic strokenomogramprediction modelprognosis

Identifiers

PMID42609232
PMCPMC13477958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.