ArticleAnnals of medicine2026
Imaging-identified round window niche veil and intratympanic therapy efficacy in sudden sensorineural hearing loss.
Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIntratympanic (IT) therapy is a common procedure to deliver drugs into the cochlear for the treatment of inner ear diseases. Round window niche veil (RWNV) is an extra anatomical barrier potentially impending drug delivery. However, RWNV's identification is neglected, and its effect on IT efficacy awaits investigation.
methodsPatients with unilateral sudden sensorineural hearing loss (SSNHL), undergoing temporal bone HRCT examination and initiating IT therapy were enrolled and followed up for 30 days. Participants were independently assessed and identified into RWNV
resultsA total of 169 patients (44.4 ± 12.6 yr; 52.1% females) were included and stratified into RWNV
conclusionsRWNV identified by a HRCT-based workflow is independently associates with inferior IT therapy efficacy in SSNHL. Pre-treatment imaging assessment may help to predict potential benefits from IT therapy.
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