ArticleJACC. Case reports2026
Acute Myocarditis as an Immune-Mediated Complication of Mpox Infection.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Myocarditis in Mpox Infection: An Uncommon Complication, a Familiar Diagnostic Challenge.JACC. Case reports · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac involvement is an uncommon and incompletely characterized complication of mpox infection. CASE SUMMARY: A 32-year-old man with well-controlled HIV and polymerase chain reaction-confirmed mpox developed acute chest pain days after a vesiculopustular rash. High-sensitivity troponin I peaked at 12,717 ng/L with elevated inflammatory markers. Coronary and embolic causes were excluded. Cardiac magnetic resonance (CMR) demonstrated lateral-wall edema on T2-weighted imaging and nonischemic late gadolinium enhancement with preserved ejection fraction, satisfying the updated Lake Louise Criteria. He recovered fully with supportive care. DISCUSSION: Mpox-associated myocarditis has predominantly been reported in young, largely immunocompetent men, including some with well-controlled HIV. The mechanism remains uncertain; immune-mediated injury and direct viral involvement both remain possible. This case underscores multiparametric CMR as a noninvasive diagnostic tool that may obviate endomyocardial biopsy in hemodynamically stable patients. TAKE-HOME MESSAGES: Mpox can cause acute myocarditis in immunocompetent patients. Multiparametric CMR enables noninvasive confirmation and may spare selected patients from endomyocardial biopsy.
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