Evidence map›Paper›PMID 42608695›Full record

ArticleGut pathogens2026

Demographic characteristics and associated conditions in enteropathogenic Escherichia coli positive patients.

Heather Lusby, Stacy G Beal, Kenneth H Rand

Abstract read
In one paragraph

Article in Gut pathogens, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Heather LusbyDivision of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville. FL 32610, USA.
Stacy G BealDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, 32610, USA.
Kenneth H RandDivision of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville. FL 32610, USA. kenrand@ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have examined the epidemiology and risk factors of Enteropathogenic Escherichia coli (EPEC); however, few have focused on the adult population. This study aimed to determine if EPEC was associated with certain patient populations or characteristics. We reviewed 792 hospitalized adults and children with symptomatic diarrhea who tested positive for EPEC on the BioFire Gastrointestinal (GI) Pathogen Panel and compared with symptomatic patients with no targets detected on the same panel as controls.

resultsIn the adult group the EPEC positive actual length of stay (LOS) was 13.5 days CI 95% [4.6,22.2] vs. 9.3 days CI 95% [7.9,10.5] (p = 0.14) for the control group, while in the pediatric population, both expected and actual LOS were actually longer in the EPEC negative patients than the EPEC positive patients (p ≤ 0.01 for both). In adults, 31.4% of EPEC positive patients had a past medical history of autoimmune disease, compared to 19.2% (p = 0.03) in the control group, after controlling for multiple variable testing.

conclusionTo our knowledge, this association between EPEC and autoimmune disease has not been previously reported and could be mediated by gut dysbiosis, suggesting avenues for follow up studies.

Indexed as

Autoimmune diseaseEnteropathogenic E. coliEPECGut dysbiosis

Identifiers

PMID42608695
PMCPMC13483709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.