Evidence map›Paper›PMID 42608492›Full record

ReviewPlanta2026

Dexamethasone-inducible LhGR/pOp system: simple and flexible spatiotemporal control of gene expression.

Zuzanna Majewska, Grzegorz Jursza, Alicja Dolzblasz

Abstract readReview
In one paragraph

Review in Planta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zuzanna MajewskaDepartment of Plant Developmental Biology, University of Wroclaw, Wroclaw, Poland.
Grzegorz JurszaDepartment of Plant Developmental Biology, University of Wroclaw, Wroclaw, Poland.
Alicja DolzblaszDepartment of Plant Developmental Biology, University of Wroclaw, Wroclaw, Poland. alicja.dolzblasz@uwr.edu.pl.ORCID http://orcid.org/0000-0002-9540-4694

Funding

Centre of Excellence and Applied Sport Science Research, Queensland Academy of Sport BPIDUB.4610.174.2022funding provided by the Department of Plant Developmental Biology 501/73/10110/MPK 2599150000/2026
6 · The paper itself

Abstract

MAIN

conclusionOur review illustrates how the dexamethasone-inducible LhGR/pOp system has been used across numerous tissues/organs and plant species, and summarizes the resources and inducer application procedures established to date. The establishment of groundbreaking molecular biology tools has enabled the rapid advancement of research based on the model plant Arabidopsis, which currently strongly benefits non-model but economically important species. Spatiotemporal control of transgene expression via the chemically inducible system GR-LhG4/pOp has proven to be a particularly powerful, universal and non-invasive experimental approach. This review characterizes the mechanism of action of GR-LhG4/pOp and synthesizes information on available GR-LhG4 transgenic lines and inductor (dexamethasone) application procedures across various plant tissues. Moreover, feasible experimental approaches are depicted that range from classical ones aiming at selected genes overexpression or silencing to highly innovative ones, like those integrating the GR-LhG4/pOp system with CRISPR-Cas for targeted ablation of specific cell types. Information about the existing GR-LhG4/pOp lines from non-Arabidopsis plants is also provided, in hope that this sophisticated but universal research tool will become more exploited in crop research.

Indexed as

ArabidopsisArabidopsis ProteinsDexamethasoneGene Expression Regulation, PlantPlants, Genetically ModifiedArabidopsis ProteinsDexamethasoneArabidopsisDexamethasoneInduction systemsLhGR/pOpNon-model plantsResources

Identifiers

PMID42608492
PMCPMC13481485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.