ReviewJournal of perinatology : official journal of the California Perinatal Association2026
Antidepressants and breastfeeding behaviors: a systematic review.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess whether antidepressant exposure during pregnancy or postpartum is associated with changes in breastfeeding behaviors STUDY
designSystematic review of interventional and observational studies; outcomes grouped as initiation/status at discharge, preterm/NICU contexts, duration, and nighttime feeding.
resultsLate-pregnancy exposure was consistently associated with lower initiation and reduced breastfeeding at discharge. In settings with intensive lactation support - such as among mothers of preterm infants or in NICUs-differences between exposed and unexposed dyads were small or nonsignificant. Effects on duration were context-dependent: in countries with high baseline breastfeeding, antenatal exposure was not linked to shorter duration and sometimes coincided with less early cessation; where baseline rates were lower, exposure was associated with earlier cessation. Evidence on nighttime feeding was sparse.
conclusionWhen antidepressant treatment is indicated, optimizing breastfeeding requires integrated perinatal care combining psychiatric monitoring, individualized medication counseling, and proactive lactation support. Prospective studies disentangling pharmacological from contextual effects are needed.
Identifiers
42608444What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.