Evidence map›Paper›PMID 42607118›Full record

ArticleCirculation2026

Activation of Glucose-6-Phosphate Dehydrogenase Promotes Cardiomyocyte Cell Cycle.

Fan Li, Yura Son, Huiliang Qiu, Andrew Zhang, Hongyu Qiu, Wuqiang Zhu

Abstract readLetter
In one paragraph

Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fan LiDepartment of Cardiovascular Medicine, Physiology, and Biomedical Engineering, Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Scottsdale, AZ (F.L., Y.S., H.Q., A.Z., W.Z.).ORCID 0000-0002-4073-4493
Yura SonDepartment of Cardiovascular Medicine, Physiology, and Biomedical Engineering, Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Scottsdale, AZ (F.L., Y.S., H.Q., A.Z., W.Z.).
Huiliang QiuDepartment of Cardiovascular Medicine, Physiology, and Biomedical Engineering, Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Scottsdale, AZ (F.L., Y.S., H.Q., A.Z., W.Z.).ORCID 0000-0001-8625-8974
Andrew ZhangDepartment of Cardiovascular Medicine, Physiology, and Biomedical Engineering, Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Scottsdale, AZ (F.L., Y.S., H.Q., A.Z., W.Z.).ORCID 0009-0006-0254-9955
Hongyu QiuDepartment of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ (H.Q.).
Wuqiang ZhuDepartment of Cardiovascular Medicine, Physiology, and Biomedical Engineering, Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Scottsdale, AZ (F.L., Y.S., H.Q., A.Z., W.Z.).ORCID 0000-0001-5217-7789

Funding

Cardiomyocyte Non-autonomous Factors and Cardiac Regeneration in Large MammalsR01HL156855 · NHLBI · MAYO CLINIC ARIZONA · PI Wuqiang Zhu · 2022 to 2026
$3.3M
Strategies to Enhance Engineered Heart Tissue Based Myocardial RepairR01HL162747 · NHLBI · MAYO CLINIC ARIZONA · PI Jingwei Xie, Wuqiang Zhu · 2023 to 2026
$2.9M
Electrically Conductive Stem Cell Derived MicroEngineered Heart Tissue for Regeneration of Injured MyocardiumR01HL172784 · NHLBI · MAYO CLINIC ARIZONA · PI Mehdi Nikkhah, Wuqiang Zhu · 2024 to 2026
$2.0M
Myocardial Repair with a Novel Engineered Cardiac Muscle PatchR01HL142627 · NHLBI · MAYO CLINIC ARIZONA · PI ZHU, WUQIANG · 2019 to 2022
$1.7M
Programmed Cell Death 4 in Doxorubicin-Induced CardiotoxicityR01HL180393 · NHLBI · MAYO CLINIC ARIZONA · PI Shu Wang, Wuqiang Zhu · 2025 to 2026
$1.3M
Myocardial Repair with a Novel Engineered Cardiac Muscle PatchR56HL142627 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHU, WUQIANG · 2018 to 2018
$371k
NHLBI NIH HHS R01 HL142627NHLBI NIH HHS R01 HL156855NHLBI NIH HHS R01 HL162747NHLBI NIH HHS R01 HL172784NHLBI NIH HHS R01 HL180393NHLBI NIH HHS R56 HL142627
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiac myocytecell cycleglucosephosphate dehydrogenaseheart

Identifiers

PMID42607118
PMCPMC13483306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.