Evidence map›Paper›PMID 42606802›Full record

ArticleHealth care analysis : HCA : journal of health philosophy and policy2026

On the Concept of Existential Disease.

Bjørn Morten Hofmann

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Article in Health care analysis : HCA : journal of health philosophy and policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bjørn Morten HofmannCentre for Medical Ethics, University of Oslo, Oslo, Norway. b.m.hofmann@medisin.uio.no.ORCID https://orcid.org/0000-0001-6709-4265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Is "existential disease" a meaningful concept? This study scrutinizes six arguments in support of the concept. First, putative existential diseases are already discussed in the academic literature, including existential neurosis and existential OCD. Second, existential disease may be understood as occurring in the absence of "existential health," a notion that has received increasing scholarly attention. Third, the very practices of diagnosing "existential suffering" and providing "existential therapy" appear to entail a concept of existential disease. Fourth, in the same way as physical and mental suffering corresponds to physical and mental disease, existential suffering corresponds to existential disease. Fifth, existential suffering arguably falls under several traditional definitions of disease, thereby supporting the legitimacy of the concept of existential disease. Sixth, medical interventions such as palliative sedation and assisted dying in response to existential suffering-interventions typically reserved for disease-seem to presuppose an existential form of disease. Although most of these arguments face important objections, certain conceptions of disease do warrant the category of existential disease. Nonetheless, there is a substantial risk of medicalizing existential concerns, and it is not clear that framing existential suffering as disease is the best way to respond to those who suffer existentially, especially given that health professionals may not be well equipped to address such forms of distress. Hence, more and better arguments are needed to ascertain the concept of existential disease.

Indexed as

ConceptDefinitionDiseaseDistressExistentialSuffering

Identifiers

PMID42606802

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.