ArticleBioprocess and biosystems engineering2026
Application of dielectric spectroscopy combined with simple linear and multivariate modelling for in-line monitoring of biomass concentration in E. coli cultures.
Article in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Biomass concentration is a crucial parameter while monitoring Escherichia coli bioprocesses. Real-time monitoring of this attribute is preferable to discrete measurement, as it immediately detects deviations, reduces sampling efforts and thereby minimizes the risk of contamination. Therefore, the potential of dielectric spectroscopy for continuous monitoring of E. coli cultures was investigated. Two datasets were acquired across culture batches in a benchtop bioreactor: ∆ permittivity and the dielectric spectrum. For each batch, variations in ∆ permittivity followed the OD
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