Evidence map›Paper›PMID 42606544›Full record

ArticlePediatric cardiology2026

Clinical and Cardiac Magnetic Resonance Imaging Findings in Pediatric Patients with Recurrent Viral Myocarditis.

Danish Vaiyani, Andrea L Jones, Kevin K Whitehead, David M Biko, Sara L Partington, Kathryn M Restaino, Matthew A Harris, Kimberly Y Lin, Mark A Fogel

Abstract read
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In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danish VaiyaniDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA. Vaiyanid@chop.edu.ORCID http://orcid.org/0000-0003-2710-1779
Andrea L JonesDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Kevin K WhiteheadDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
David M BikoDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Sara L PartingtonDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Kathryn M RestainoDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Matthew A HarrisDivision of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Kimberly Y Lin *Division of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Mark A Fogel *Division of Cardiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children and adults can suffer recurrence of myocarditis months to years after their initial presentation; however predictors of recurrence in the pediatric population have not been described to date. We sought to describe cardiac magnetic resonance (CMR) imaging findings and predictors of recurrence in a pediatric cohort. A retrospective cohort study of patients < 21 years, clinically diagnosed with acute myocarditis and who underwent CMR within 14 days of initial presentation was performed. Mann-Whitney U test and Fisher's exact test were used to compare those who fully recovered versus those with recurrence. Of 85 patients who met inclusion, median age 16.3 years (IQR 14.3, 17.5), 72 fully recovered, 5 had recurrence, 5 were lost to follow up and 3 progressed to chronic dilated cardiomyopathy. Median time to CMR following presentation was 2 days (IQR 2, 4) and time to recurrence was 681 days (IQR 386, 855). Compared to those who recovered, patients with recurrence had similar indices of ventricular function, volume, strain and tissue characterization including T1 mapping and T2 mapping on their initial and follow up CMR. Myocarditis may recur in a small proportion of children. These children have similar findings on initial and follow up CMR as those who recover. Further work is needed to identify useful predictors of recurrence in children.

Indexed as

Magnetic resonance imagingMyocarditisOutcomesPediatric cardiologyRecurrence

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.