ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Impact of Coagulopathy at Admission on Perioperative Blood Transfusion in Acute Type A Aortic Dissection.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
IntroductionSurgery for acute type A aortic dissection (ATAAD) may expose patients to major bleeding and massive transfusion. We assessed the impact of coagulopathy upon admission, before surgery, on perioperative transfusion requirements and clinical outcomes.MethodsWe conducted a retrospective single-center study including consecutive patients undergoing emergency surgical aortic repair for ATAAD from August 2017 to July 2022 in a tertiary referral center. We assessed the association between coagulopathy at hospital admission, defined by an International Normalized Ratio (INR) >1.2, and perioperative transfusion requirements and clinical outcomes.ResultsAmong 133 included patients operated for ATAAD, 36 (27%) had coagulopathy at admission. Compared with non-coagulopathic patients, they more frequently presented with preoperative shock and had higher lactate levels at admission. Coagulopathic patients received more intraoperative red blood cell (RBC) transfusions (4 [1.7-7] vs 2 [0-4] units, p=0.009), fresh frozen plasma (FFP) (4 [2.8-6] vs 3 [2-4] units, p=0.028), platelets (5.3 [3.7-8.2] vs 4 [3.2-5.5] x10
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