Evidence map›Paper›PMID 42606138›Full record

ArticleRespiratory care2026

Evaluating the Association of Extubation Readiness Testing Performance Variables With Reintubation After Pediatric Cardiac Surgery.

Matthew J Foglia, Elizabeth J Thompson, Jennifer I Sherwin, Veerajalandhar Allareddy, Alexandre T Rotta, Andrew G Miller

Abstract read
In one paragraph

Article in Respiratory care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew J FogliaDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-2620-0233
Elizabeth J ThompsonDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Jennifer I SherwinDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Veerajalandhar AllareddyDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Alexandre T RottaDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Andrew G MillerDrs. Foglia, Thompson, Sherwin, Allareddy, and Rotta and Mr. Miller are affiliated with the Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-9110-9156

Funding

Real-world Data Enables Pharmacokinetic/Pharmacodynamic-based Drug Dosing in Critically Ill ChildrenK23HD116971 · NICHD · DUKE UNIVERSITY · PI Elizabeth Jaclyn Thompson · 2025 to 2026
$375k
NICHD NIH HHS K23 HD116971
6 · The paper itself

Abstract

backgroundPatient performance on extubation readiness tests (ERTs) informs the decision to extubate after cardiac surgery. ERT pass criteria at our center include age-based breathing frequencies and weight-adjusted tidal volumes (V

methodsThis was an observational, retrospective cohort study involving children <18 years of age receiving invasive mechanical ventilation for >24 h after cardiac surgery for Society of Thoracic Surgery (STAT) Mortality category ≥3 from May 2022 to April 2024. The primary outcome was extubation failure. The secondary outcome was the interval between the first passed ERT and extubation. Factors associated with re-intubation were explored using univariate and multivariable analyses.

resultsTwo hundred sixty-eight subjects met inclusion criteria with a median (interquartile range) age of 58.5 (6.1-210.2) days and weight of 4.2 (3.3-7.5) kg. Thirty (11.2%) subjects experienced extubation failure. These subjects had a higher breathing frequency during the ERT (42 [36-52] vs 36 [28-44] breaths/min,

conclusionsThere was no association between the final ERT breathing frequency, V

Indexed as

airway extubationcongenital heart diseaseextubation readiness testingmechanical ventilation

Identifiers

PMID42606138
PMCPMC13586949

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.