ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling.
Lei Gao, Qinying Han, Yunpeng Wang, Xuemei Li, Bofang Wang, Baohong Gu, Weidong Li, Lin Xiang, Ying Zhang, Hao Chen
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Qinying HanThe Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, People's Republic of China.
Yunpeng WangThe Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, People's Republic of China.
Xuemei LiThe Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, People's Republic of China.
Bofang WangCancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Baohong GuCancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Weidong LiThe Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, People's Republic of China.
Lin XiangThe Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, People's Republic of China.
Ying ZhangDepartment of Laboratory Medicine, the First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Funding
Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital CY2023-QN-A01Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital CY2023-ZD-01Gansu Province Postgraduate, Innovation Star Program 2025CXZX-115Gansu Province Science and Technology Plan Project 24JRRA373General Project of Gansu Province Joint Research Fund 24JRRA929Key Project of Science and Technology in Gansu province 22ZD6FA054Key Talents Project of Gansu Province 2019RCXM020Major scientific research project for scientific and technological innovation in the health industry of Gansu Province GSWSZD-2024-17National Natural Science Foundation of China 82160129National Natural Science Foundation of China 82473266National Natural Science Foundation of China 82560488
6 · The paper itselfAbstract
Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer. F7 was highly expressed in tumor tissues and closely associated with lymph node metastasis, poor prognosis, and reduced CD8
Indexed as
extracellular matrixgastric cancerimmune checkpoint inhibitorimmunosuppressiontumor microenvironment (TME)
Identifiers
PMID42606136
PMCPMC13479850
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