Evidence map›Paper›PMID 42605860›Full record

ArticleThe Cochrane database of systematic reviews2026

Gemcitabine-based chemotherapy for advanced biliary tract carcinomas.

Atalel F Awedew, Assefa Fentahun Emrie, Mihretu Jegnie, Luis Morales, supported by the Cochrane Hepato-Biliary Group

Abstract read
In one paragraph

Article in The Cochrane database of systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atalel F AwedewDepartment of Surgery, Debre Tabor University, Debre Tabor, Ethiopia.ORCID https://orcid.org/0000-0001-8611-599X
Assefa Fentahun EmrieDepartment of Surgery, Debre Berhan University, Debre Berhan, Ethiopia.
Mihretu JegnieDepartment of Biomedical Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Luis MoralesVascular Surgery & Endovascular Therapy, University of Colorado Anschutz Medical Campus, Colorado, Colorado, USA.
supported by the Cochrane Hepato-Biliary Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis is a protocol for a Cochrane review (intervention). The objectives are as follows: To assess the benefits and harms of intravenous administration of gemcitabine monotherapy or gemcitabine-based combination chemotherapy versus placebo or non-gemcitabine-based chemotherapy in people with advanced biliary tract carcinomas.

Indexed as

Antimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsBiliary Tract NeoplasmsGemcitabineDeoxycytidineHumansRandomized Controlled Trials as TopicSystematic Reviews as TopicAntimetabolites, AntineoplasticDeoxycytidineGemcitabine

Identifiers

PMID42605860
PMCPMC13479367

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.