Evidence map›Paper›PMID 42605671›Full record

ArticleJournal of integrative bioinformatics2026

The DSMZ Digital Diversity Annotation Hub: a pipeline for database expansion via text mining and human curation.

Emanuel Quadros, Lorenz C Reimer, Julia Koblitz

Abstract read
In one paragraph

Article in Journal of integrative bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emanuel QuadrosLeibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.ORCID https://orcid.org/0000-0003-0002-3635
Lorenz C ReimerLeibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.ORCID https://orcid.org/0000-0002-7805-0660
Julia KoblitzLeibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.ORCID https://orcid.org/0000-0002-7260-2129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintaining scientific databases that depend on continuous curation of research literature often requires labor-intensive, slow, and error-prone annotation processes. To address these challenges, we present a pipeline that integrates text mining with expert supervision to support database expansion. Using the BRENDA enzyme database as a case study, we compiled a relation extraction dataset by aligning document-level annotations with literature references through distant supervision. We then developed a neural model that performs entity recognition and relation classification, enabling the extraction of enzyme-strain associations from full-text articles. To close the loop between machine learning and expert curation, we designed a web-based interface that allows annotators to review and refine predicted relations. While preliminary, our initial experiments show the potential of combining weak supervision and human-in-the-loop validation to accelerate the integration of literature-derived information into knowledge bases.

Indexed as

Databases, FactualData CurationData MiningBiocurationHumansMachine Learningdata annotationdatabase expansionnamed-entity recognitionrelation extractiontext mining

Identifiers

PMID42605671
PMCPMC13526447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.