ReviewNigerian medical journal : journal of the Nigeria Medical Association
Impact of Progesterone Therapy on Treatment Outcomes and Recurrence After Hysteroscopic Polypectomy.
Review in Nigerian medical journal : journal of the Nigeria Medical Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: One of the concerns after transcervical resection of endometrial polyps (TCRP) is the recurrence of polyps post-surgery. Some studies have shown that hormone therapy with progesterone may reduce the risk of recurrence. This clinical trial aimed to investigate the effect of progesterone treatment after hysteroscopic polypectomy. Methodology: In this clinical trial, 40 patients diagnosed with endometrial polyps were randomly and equally assigned to two groups: intervention and control. TCRP surgery was performed for both groups. In the intervention group, medroxyprogesterone was administered one week after surgery at a dose of 10 mg twice daily from the 5th day of the menstrual cycle for 21 days, over four cycles. The recurrence rate at 3 and 6 months post-surgery, endometrial thickness, hemoglobin levels, and menstrual status before and six months after surgery were compared between the two groups. Results: None of the patients had a recurrence of endometrial polyps in the first three months, while three patients in the control group had a recurrence six months post-surgery (Relative Risk (RR) = 7.0, CI: 0.38-12.73). Regarding menstrual disorders, one patient in the control group had a menstrual disorder in the first three months (RR = 3.0, CI: 0.12-69.51), while six months post-surgery, 11 patients in the control group and one patient in the intervention group had menstrual disorders (RR = 11.55, CI: 1.63-81.45). Endometrial thickness six months post-surgery was significantly lower in the intervention group (5.5 ± 1.2 mm vs. 8.0 ± 2.5 mm, P = 0.001). The mean hemoglobin level six months post-surgery was higher in the intervention group, but it was not statistically significant. Conclusion: Progesterone administration after TCRP surgery may be effective due to improved menstrual status, reduced endometrial thickness, and possibly lower recurrence rates of endometrial polyps.
Indexed as
Identifiers
42605458PMC13477703What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.